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KMID : 0359720070250030393
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Journal of the Korean Neurological Association
2007 Volume.25 No. 3 p.393 ~ p.397
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Relapsing Herpes Simplex Encephalitis
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Jang Woo-Young
Oh Ki-Wook
Kim Hyun-Young
Han Gwang-Su
Kim Hee-Tae
Kim Seung-Hyun
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Abstract
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Herpes simplex encephalitis (HSE) is the most common type of viral encephalitis and a fourteen day administration
of acyclovir is well-known as the treatment of choice for HSE. Occasionally HSE relapses, but rarely with acyclovir
treatment. We report a case of relapsing HSE after treatment with acyclovir for 14 days. Our case suggests that
patients with progressive high signal intensities in diffusion-weighted brain MRIs might need longer antiviral
therapy over 14 days for preventing the relapse of herpes simplex encephalitis.
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KEYWORD
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Herpes simplex encephalitis, Relapse, Diffusion weighted image
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